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Bipolar Disorder  -Treatment

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Practice Guideline for the Treatment of Patients With Bipolar Disorder (Revision) American Psychiatric Association April 2002

Evidence-based guidelines for treating boplar disorder: recommendations from the British Association for Psychopharmacology pdf  25 pages  Consider long-term treatment following a single severe manic episode (i.e. diagnosis of bipolar I disorder) because, although there is no controlled evidence, the natural history of the illness implies that preventing early relapse may lead to a more benign illness course

Old guidelines
Practice Guideline For The Treatment Of Patients With Bipolar Disorder American Psychiatric Association


Long-term Management of Bipolar Disorder Medscape CME Sept 2003 Charles Bowden, MD; Vivek Singh, MD
Ninety percent of patients will have recurrent manic episodes. Good section on various factors that can precipitate mania including medical conditions and drugs as well as other factors.


American Psychiatric Association 155th Annual Meeting  Medscape Coverage

New Developments in the Treatment of Bipolar Disorder , MD  CME June 2002 treatment regimens need to be efficacious but also well tolerated, so that treatment adherence will remain high

Customizing Care for Patients With Bipolar Disorder Charles L. Bowden There is evidence that side effects of some drugs that are unlikely to be well tolerated during maintenance therapy may be either adequately tolerated or actually beneficial during a full manic episode

New Research in Bipolar Disorder Treatments and Practice Patterns John J. Spollen III, MD


Annals of Internal Medicine  Psychopharmacologic Treatment Strategies for Depression, Bipolar Disorder, and Schizophrenia 2 January 2001 Volume 134 Number 1 clear and concise (Now only available to eligible registered users)
Archived at  Internet Archive  type in
 http://www.annals.org/issues/v134n1/full/200101020-00013.html

Choose  Jan or Mar 2001

The 'Art' of Treating Bipolar Depression Bipolar Disorders Letter 02/99  research by Zornberg and Pope (1993) that found a 70% response rate for lithium as an acute treatment for bipolar disorder compared to a 40% response rate for unipolar depression
go to Internet Archive Internet Collections
type in
http://www.mhsource.com/bipolar/bp9902art.html
 

Bipolar Depression and Rapid Cycling: The Latest Pharmacologic Strategies Medscape July, 2002 The three goals of mood stabilizer therapy is to treat manias without causing or worsening them, treat depressions without causing or worsening them and effective prophylaxis for manias and depressions,said Goldberg. I'm hard pressed to find one agent that does all three of these things in an excellent way, he added


Treating Bipolar Disorder- Toward the Third Millenium I
Treating Bipolar Disorder- Toward the Third Millennium II Psychiatric Times Feb and April 2001

STEP-BD (Systematic Treatment Enhancement Program for Bipolar Disorder) NIMH is sponsoring a  5 year study at 18 American sites to determine best treatment for bipolar  clients. It is looking for participants now. Along with medications, it will be looking at efficacy of psychotherapy type interventions.. Participants need to pay for treatment as they do currently. Free study medication is provided to those enrolled in Randomized Care Pathways. Funding to defray the cost of uninsured psychosocial treatments is available, based on need.

Clinical Management of Bipolar Disorder Medscape Sept 20, 2002 CME includes Mood Disorders Questionnaire  Other symptoms of manic, mixed and depressive episodes, which are not listed in DSM-IV-TR, include anxiety, hostility, impulsivity, violence, poor insight, confusion, memory impairment, and sensory hyperacuity.

 Medication treatment of Bipolar Disorder 2000 . The Expert Consensus Guideline Series: Medication Treatment of Bipolar Disorder 2000.  pdf files which  need Adobe Acrobat to view it. (104 pages and so takes a very long time to load)

New Research Studies on Treatments for Bipolar Disorder  Charles L. Bowden, MD American Psychiatric Association 153rd Annual Meeting Day 4 - May 17, 2000 medscape

Building Foundations Toward Recovery in Bipolar Disorder
Martin L. Korn, MD Interesting : By employing a tyrosine and phenylalanine-free amino acid drink, dopamine-sensitive prolactin levels were decreased within 6 hours.[11] The mixture also was effective in diminishing manic symptoms in 20 inpatients during a manic episode.[12] Use of an amino acid drink as a supplemental treatment in acute mania is currently in development.

 Psychopharmacologic Treatment Strategies for Depression, Bipolar Disorder and Schizophrenia  Annals of Internal Medicine

A Summary of Clinical Issues and Treatment Options Bipolar Bipolar Disorder Sub-Committee Canadian Network for Mood and Anxiety Treatments (CANMAT) April 1997
Alternative link Canmat

Management of Bipolar Disorder American Family Physician Sept.15,2000 It includes a table of causes of Secondary Mania. (Table 4 implies that it is okay to use buproprion or an SSRI alone to treat Bipolar and is based on 1996 guidelines)

Bipolar Disorders: Clinical Complexities, Current Challenges by Michael Gitlin, M.D.the stresses of both life itself and the specific stresses associated with having a major mood disorder can in turn trigger further episodes in a vicious circle (with more stress leading to more episodes leading to more stress, etc

Charting the Course of Bipolar Illness and Its Response to Treatment  Medscape May 1998 (fixed link)

New Approaches to Bipolar Disorder Medscape December 13, 2000 CME Gary Sachs, MD (Assistant Professor of Psychiatry, Harvard Medical School, and Founder and Director of the Harvard Bipolar Research Program) (fixed link)

The Expert Consensus Guideline Series: Treatment of Bipolar Disorder

Expert Consensus Treatment Guidelines for Bipolar Disorder: A Guide for Patients and Families
Don't be put off by the guide for Patients and Families label. This file is more in depth than the usual. 

Clinical Practice Guidelines for Bipolar Disorder from the Department of Veterans Affairs Mark S. Bauer, M.D.; Ann M. Callahan, M.D.; Chowdary Jampala, M.D.; Frederick Petty, Ph.D., M.D.; Martha Sajatovic, M.D.; Vicky Schaefer, R.N.; Byron Wittlin, M.D.; and Barbara J. Powell, Ph.D.

Treatment of Bipolar Disorder

Topic: Current Treatments in Bipolar Disorder Moderator - Norman Sussman, MD Discussants - Gregory Asnis, MD; Charles L. Bowden, MD-A good discussion on the various drugs used in treating Bipolar Disorder

Update on the Treatment of Bipolar Disorder Mood Stabilizer Combinations medinet ca,1999Based on an article published in the American Journal of Psychiatry1998; 155(1):12-21

Stanley Center for the Innovative Treatment of bipolar disorder

Assessment and Treatment of Bulimia Nervosa This article includes a section on comorbidity of disorders

Bipolar Disorders  Meeting: Researchers Find New Approach To Treating Bipolar Disorder

Choosing the Appropriate Therapy for Bipolar Disorder medscape  Aug 1997 (new link)

Treatment of bipolar affective disorder A H Young, Karine A N Macritchie, and J R Calabrese BMJ 2000; 321: 1302-1303.   EDITORIAL 

Bipolar II - Treatment Appendices 

DG DISPATCH - APA MEETING- Combination Treatment Often Necessary For Bipolar Disorder May 1999


Texas Medication Algorthm Project  238page  pdf  June 1, 1999 Includes assessment forms
Tima Procedural Manual 76 page pdf August, 2002

High Treatment Noncompliance Among BD Patients With Personality Disorders Feb 2001 Bipolar Disorders Letter higher noncompliance among the younger, those with comorbid substance abuse and Axis 11 personality disorders. 

Study Seeks Better Care for Bipolar Patients in Public Sector medscape jul 2001 (newlink)

Bipolar affective disorder-left out in the cold Richard Morriss, Max Marshall, and Amanda Harris BMJ 2002; 324: 61-62.

Current Treatments of Agitation and Aggression Medscape May28,2002 CME


Canadian Journal of Psychiatry Aug,1997 supplement articles. all are in pdf

The Treatment of Bipolar Disorder: Review of the Literature, Guidelines, and Options V Kusumakar, LN Yatham (Introduction and preamble)

The Foundations of Effective Management of Bipolar Disorder V Kusumakar, LN Yatham, DRS Haslam, S Parikh, R Matte, V Sharma, PH Silverstone, SP Kutcher, S Kennedy

Psychosocial Interventions as an Adjunct to Pharmacotherapy in Bipolar Disorder SV Parikh, V Kusumakar, DRS Haslam, R Matte, V Sharma, LN Yatham

Treatment of Mania, Mixed State, and Rapid Cycling V Kusumakar, LN Yatham, DRS Haslam, SV Parikh, R Matte, PH Silverstone, V Sharma

Bipolar Depression: Treatment Options LN Yatham, V Kusumakar, SV Parikh, DRS Haslam, R Matte,
V Sharma, S Kennedy


Continuation and Prophylactic Treatment of Bipolar Disorder V Sharma, LN Yatham, DRS Haslam, PH Silverstone, SV Parikh, R Matte, SP Kutcher, V Kusumakar


Not working
MSN Canada - How Is Bipolar Disorder Treated Well  Connected June 1999 http://health.msn.ca/content/dmk/dmk_article_5461966
Update on Bipolar Disorder: Epidemiology, Etiology, Diagnosis, and Prognosis
How is Bipolar Disorder Treated? MebMDHealth June 1999 (temporarily unavailable)