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Prozac/Fluoxetine Zoloft/Sertraline Paxil/Paroxetine Venlafaxine/Effexor
  Reboxetine Nefazadone/Serzone Citalopram/Celexa
Zyprexa/Olanzapine Lithium Neurontin Gabapentin
Topiramate/Topomax Luvox/fluvoxamine Buproprion/Wellbutrin  

The activating antidepressants include: the SSRI's (Prozac, etc), Wellbutrin, Effexor, protryptyline, and the MAOIs.

The sedating antidepressants include: Serzone, Trazodone, Remeron, amitriptyline, doxepin, and trimipramine.

 

Antidepressant treatment of other conditions

Antidepressants for More than Depression about.com quick read overview

Don't Give Up Too Quickly When Treating OCD Medscape (not working)
Five antidepressant medications have been well studied and have proven effective in treating OCD: clomipramine 100-240 mg/day, fluoxetine 40-80 mg/day, sertraline 100-200 mg/day, fluvoxamine 100-300 mg/day, and paroxetine 40-60 mg/day. Also venlafaxine at 150-375 mg/day appeared to help OCD in small, uncontrolled studies.

Social Anxiety Disorder: A Treatable Condition Medscape Selective serotonin reuptake inhibitors (SSRIs) such as paroxetine, sertraline, fluvoxamine, and fluoxetine have all been shown to work in alleviating the symptoms of SAD/social phobia.In more resistant cases of SAD, the monoamine oxidase inhibitor (MAOI)phenelzine can be useful (not working)

Antidepressants Appear Useful in Some PTSD Cases Medscape Dr.Mellman, director of the posttraumatic stress disorder (PTSD) program at the Veterans Affairs Medical Center in Miami at the annual meeting of the American Psychiatric Association..(not working)

SSRIs an Effective First-Line Treatment for Severe PMS medscape reuters Sept 29,2000

DG DISPATCH- APA- Treating Premenstrual Dysphoric Disorder 05/23/2000

Migraine, Cluster, Trigeminal Neuralgia, and Mood Disorders - Introduction medscape cme Includes an explantion on how various anti-convulsants work.(not working)

Neurology Treatment Updates - Anticonvulsant Therapy medscape  CME still there but expired

Paroxetine/Paxil 

APA- Paxil (Paroxetine) Effective in Treating Generalized Anxiety Disorder
DG DISPATCH - AACAP: Paroxetine Ineffective For Adolescent Unipolar Depression
Nursing Mothers With Depression Can Safely Take Paxil, Study Shows 
PSYCHIATRY UPDATE For pregnant-depressed, paroxetine better Medical Post Nov.7, 2000
Paroxetine safer for patients with rheumatoid arthritis than amitriptyline News @ PharmiWeb 2001-01-22
FDA Approves Paxil for Generalized Anxiety Disorder medscape Apr.16, 2001

Paxil Effective For Major Depression In Adolescents Ivanhoe July,24, 20001
Landmark Study Finds Paroxetine Effective Treatment for Adolescent Depression medscape 2001

New Help for Post-Traumatic Stress Ivanhoe Broadcast News - September 21, 2001
 

Sertraline Zoloft

 

FDA Approves Sertraline for PMDD May 17, 2002 medscape Reuters The FDA said it had approved two supplementary new drug applications for Zoloft as a PMDD treatment: one for daily dosing and one for use during only the luteal phase of the menstrual cycle.

DG DISPATCH - AACAP: Sertraline Effective In Children With OCD

WebMD - FDA Approves Paxil to Treat Posttraumatic Stress Disorder Dec,2001

Sertraline Effective For Adolescent Anxiety Disorders
Children and adolescents with anxiety disorders experience a clear improvement in symptoms when treated with sertraline (50 mg).

Sertraline may be effective for PTSD
BETHESDA, MD, Oct 11 (Reuters) - A federal advisory panel Friday recommended that the Food and Drug Administration (FDA) approve Pfizer Inc.'s sertraline (Zoloft) as the first drug treatment for post-traumatic stress disorder.
Sertraline Appears Effective in Treatment of PTSD medscape May 14, 2001
Zoloft Approved for Posttraumatic Stress Disorder
More than 100 million prescriptions for Pfizer's Zoloft have bee written since its launch in 1992, helping patients with depression, obsessive-compulsive disorder, and panic disorder. Now Zoloft is the first medication to be approved for treating posttraumatic stress disorder.

Sertraline may help relieve PMS symptom
July 28, 1999: A new study suggests that the antidepressant drug sertraline (Zoloft), from Pfizer Inc., may be effective in controlling symptoms of premenstrual syndrome (PMS).

Sertraline Superior to Desipramine for Treatment of Depression Plus OCD medscape (not working)
WESTPORT, Jan 21 (Reuters Health) - The serotonin reuptake inhibitor sertraline is better tolerated and more effective than the norepinephrine reuptake inhibitor desipramine in patients with concurrent major depression and obsessive-compulsive disorder (OCD), according to findings reported in the January issue of Archives of General Psychiatry.

APA- Zoloft (Sertraline) Effective in Treating Social Phobia 05/16/2000

Sertraline Treatment of Generalized Social Phobia: A 20-Week, Double-Blind, Placebo-Controlled Study Van Ameringen et al. 158 (2) 275 abstract Am J Psychiatry 158:275-281, February 2001

Sertraline Effective for Depression in Alzheimer's Patients Nov.22,2000 medscape out of 22 women patients with both Alzheimers and major depression 6 were rated as full responders and 6 as partial responders.

Sertraline- The First SSRI To Be Approved for the Specific Treatment of Post-Traumatic Stress Disorder medscape Aug, 20019 (working)


Fluoxetine/Prozac


DG DISPATCH - ECNP: Severe PMS Can Be Treated With SSRIs
Prozac (fluoxetine) is highly effective in reducing symptoms of premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD), according to new studies.

Phentermine/fluoxetine Adds Little to the Treatment of Binge Eating Disorder Combining medication and psychotherapy for treatment of binge eating disorder appears to offer no "long-term clinical utility" over psychotherapy alone medscape reuters news Int J Eat Disord 2000;28:325-332.

Prozac Can Treat Depression of Those With Diabetes

Depressed Patients Responding Well to Once-Weekly, Enteric-Coated Fluoxetine

Fluoxetine May Be Effective Migraine Prophylaxis medscape Feb 15 ( not workiing)

Fluoxetine Improves Hot Flashes in Women With Breast Cancer Risk medscape April 2002

Fluoxetine Safe, Effective in Body Dysmorphic Disorder Medscape April 2002

 


 

Effexor/Venlafaxine

Venlafaxine Helpful in Generalized Anxiety Disorder in Children medscape May, 2002

DG DISPATCH - ECNP: Venlafaxine Relieves Anxiety Symptoms
LONDON, UK -- September 23, 1999 -- The novel antidepressant venlafaxine HCl (Wyeth Ayerst, Effexor XL in Britain, Effexor XR in the rest of the world) might be the next new weapon in doctors’ armamentarium to be used in the treatment of generalized anxiety disorder.

Extended-Release Venlafaxine Effective for Migraine and Tension-Type Headaches An extended-release formulation of the antidepressant venlafaxine is effective and safe for treating both migraine and chronic tension-type headaches, according to a report in the July/August issue of Headache medscape

Antidepressant Effexor XR (Venlafaxine) Given FDA Approval For Generalized Anxiety Disorder 07/17/2000

Study identifies effective nonhormonal remedy for hot flashes EurekAlert 14 December 2000 The Lancet Venlafaxine Hot flashes can be caused by menopause, chemotherapy and tamoxifen.

  Use of Venlafaxine for Hot Flashes medscape

Extended-Release Venlafaxine Appears Safe and Effective for Anxiety medscape July 11,2001

 


Neurontin Reduces Symptoms Of Social Phobia


Citalopram/Celexa

DG DISPATCH - ECNP:Obsessive Compulsive Disorder Responds To Citalopram Treatment Obsessive compulsive disorder responds well to citalopram, the most selective of the SSRI, according to a new study.

Citalopram Effective Treatment For Phobia Associated With Panic Disorder medscape Feb 15,2000

CNN.com - Health - Drug can help compulsive shoppers - December 12, 2000  80% of 21 patients tested with Celexa improved.

Antidepressant, Celexa (Citalopram), Produces Less Weight Gain Than Paxil (Paroxetine) Doctor's guide Dec.15,2000

Brief Report - Citalopram in Child and Adolescent Depression non activating

 


Gabapentin

Anti-Migraine And Seizure Drug, Gabapentin, May Reduce Menopausal Hot Flashes 

Gabapentin better than amitriptyline in relieving painful diabetic neuropathy News @ PharmiWeb 


Depression Drug May Help Treat Brain Diseases Lithium may some day be used to treat degenerative brain conditions such as Alzheimer's or Parkinson's diseases, researchers suggest....


Olanzapine

Olanzapine Treatment of Psychotic and Behavioral Symptoms in Patients With Alzheimer Disease in Nursing Care Facilities: A Double-blind, Randomized, Placebo-Controlled Trial Oct,2000

Disruptive Behavior in Alzheimer's Disease Reduced in Short Term by Olanzapine medscape Reuters Oct 15, 2000 Arch Gen Psychiatry 2000;57:968-976.


Psych Drug May Help Fight Obesity  October 24, 2000, Medical Post Topiramate may fight obesity and alleviate symptoms of Premenstrual dysphoric disorder

Nefazodone Benefits Vietnam Veterans With Post-Traumatic Stress Disorder medscape May 02,2000 .....at the end of the study the patients "were still symptomatic; they were just a lot better than they were."

Antidepressant shown effective in countering chronic headaches amitriptyline chronic tension-type headaches

FDA Approves Fluvoxamine for OCD in Children Nov 3,2000
Fluvoxamine effective treatment for obsessive-compulsive disorder in children
Fluvoxamine Effective Treatment For Obsessive-Compulsive Disorder in Children medscape Feb 19 2001

Ziprasidone May Be Safe Alternative for Treating Pediatric Tourette's Syndrome  medscape Feb 23,2000 An "intriguing" finding, Dr. Chappell and his team say, is the observation that ziprasidone reduced symptoms of obsessive-compulsive disorder by an average of 26% in patients with clinically significant obsessive-compulsive disorder at baseline.

Multimodal Therapy Effective in School-Refusing, Anxious, Depressed Adolescents  medscape Feb.23,2000 Imipramine plus cognitive-behavioral therapy

Quetiapine Safe, Effective in Migraine Prophylaxis medscape May 2002

Risperidone Controls Behavior in Children With Subaverage IQ Medscape Aug 2002


Wellbutrin/Zyban/buprorion


A Controlled Clinical Trial of Bupropion for Attention Deficit Hyperactivity Disorder in Adults Wilens et al. 158 (2) 282 Am J Psychiatry 158:282-288, February 2001

Buproprion May Treat ADHD in Adults medscape Feb, 2001, many adults with ADHD also suffer from depression, so giving them an antidepressant "just makes sense

Study shows promising treatment for women with low sex drive eurekalert april 18,2001


Inhibition of Hepatic P-450 Isoenzymes by Serotonin Selective Reuptake Inhibitors: In Vitro and In Vivo Findings and TheirImplications for Patient Care