FDA Approves Once-a-Week Prozac Feb.27,2001 Psycport It will be available in March. Fda didn't require proof that it was as effective as the daily version just more effective than a placebo.
Lilly's Once-Weekly Prozac Approved by FDA medscape reuters

PRI Gets Tentative Approval for Generic Prozac Capsules  medscape target date, Feb 2002

Why Prozac Is Not Always a Miracle Drug fox.news.com Why it works for some and not for others Monday, October 16, 2000

Time to onset of response to fluoxetine predicts ultimate response reuters 28.09.00 More than half the patients with major depression who respond to fluoxetine within 8 weeks start to respond within 2 weeks, and 75% respond within 4 weeks, according to a report by researchers from Massachusetts General Hospital, Boston. Patients who do not show an onset response to the drug within that time have a high probability of not responding by 8 weeks.
Time to Onset of Response to Fluoxetine Predicts Ultimate Response medscape link to same

Low-Dose Fluoxetine Effective, Well Tolerated in Adults With Major Depression Medscape Reuters Nov.28, 2000 20mg safe and effective. 

Side Effects

Guardian Unlimited They said it was safe Article about severe albeit uncommon side-effect akathisia German labeling For his/her own safety, the patient must be sufficiently observed, until the antidepressive effect of Fluctin [Prozac] sets in. Taking an additional sedative may be necessary."


Prozac Mania - Suite101.com May 9, 2000 Article on above topic but with added links. Clearly Prozac's very tangible benefits far outweigh the harm and risk of harm, but users need to be aware of those risks before they can make informed choices. 

JUDGE ALLOWS PROZAC DEFENSE  February 25, 2000 9:16 a.m. ET He had been suffering from depression, but his mental state may also have been affected by his family history of bipolar disorder and his abuse of alcohol

More on Prozac ( this site)

Lilly Halts Clinical Trials of New Antidepressant Psychiatirc news Dec.1,2000 In a startling move, clinical trials of (R)-fluoxetine, the new version of Prozac, have been halted by Lilly as concerns grow over cardiac side effects.