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News and Articles This site keeps up an extensive list of bipolar news and articles.


Hospital find may help bipolar disorder Professor Dean's research has shown that a component of the brain called the GABAa receptor is altered in people who have bipolar disorder


U-M team finds evidence of brain chemistry abnormalities in bipolar disorder 30% higher concentration of certain signaling cells may help explain, treat "manic depression 
"U-M team finds evidence of brain chemistry abnormalities in bipolar disorder "

Evidence of Brain Abnormalities in Bipolar Disorder Medscape In this study done by University of Michigan researchers, Bipolar patients had about 30% more of the cells that release dopamine, serotonin and norepinephrine

Monoamines explain manic episodes in bipolar disorders same study 

Abnormal Brain Chemistry Found in Bipolar Disorder about.com Easy to read write up of the same study. To put it simply, these patients' brains are wired differently, in a way that we might expect to predispose them to bouts of mania and depression," says Jon-Kar Zubieta, M.D., Ph.D., assistant professor of psychiatry and radiology at the University of Michigan Health System

Genetic Research Its Implications for Bipolar Disorder Arline Kaplan

Excess Monoaminergic Synaptic Terminals Associated With Bipolar I Disorder Medscape (Reuters Health) Oct 9,2000  Am J Psychiatry 2000;157:1619-1628 Abnormally high concentrations of the vesicular monoamine transporter protein (VMAT2) — and presumably monoaminergic synaptic terminals — appears to be a trait-related abnormality in patients with bipolar I disorder.


Brain Changes in Depression University of Mississippi Medical Center 4-May-99 

Depression and the Birth and Death of Brain Cells

ScienceDaily Magazine -- Sustained Use Of Anti-Depressants Increases Cell Growth And Protects Cells In The Brain   Posted 12/15/2000 

Discovery of brain phenomenon could lead to better drugs for certain mental illnesses Eukalert

Glucocorticoids and Hippocampal Atrophy in Neuropsychiatric Disorders  
 
arch of gen psych
 
BJP -- McQUADE and YOUNG 177 (5) 390 Future therapeutic targets in mood disorders: the glucocorticoid receptor 

Too Many Brain Cells Mean Mood Disorder


GABA-A Alpha-2 Receptor Subunit Proposed as Target for Antianxiety Drugs medscape reuters news Science 2000;290:131-134.

ScienceDaily Magazine -- Gene Identified That May Play Role In Psychological Disorders 

Human Emotion Processing at the Neuronal Level Investigated medscape


A genetic basis for attachment disorganization in infants 1 November 2000 eurekalert
assoiciated with genetic variations in the dopamine receptor (DRD4) gene.

Corticotropin-Releasing Hormone Receptor-2 Modulates Stress, Anxiety Responses medscape Mar 28 Nature Genetics

New Research May Mean Better Antianxiety Medications about.com


Estrogen deprivation leads to death of dopamine cells in the brain 

Brain Abnormalities Common in Survivors of Childhood Abuse medscape Dec.21, 2000 His group found that left-sided EEG abnormalities, rare in nonabused individuals, were more than twice as common as right-sided abnormalities in the abused group


Psychiatric Times
Amino Acid Precursors for Depression 
Medical Illness and Depressive Disorders

Unraveling the Riddle of Schizophrenia and Bipolar Disorder


The Co-occurence of Bipolar Disorder and Multiple Sclerosis Journal of Neurological Sciences 1999 It claims that there is an increased prevalence of bipolar disorder among MS patients but at 1.54% , the figure is inline with current occurrence estimates.Corticosteroids are well-known precipitants of mental disturbances and mood disorder. Hypomanic episodes induced by corticosteroids generally begin early during treatment, occur in particular when high doses are administered, and resolve without additional medication within a couple of days after stopping the treatment