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Using the Atypical Antipsychotic Agents in Children and Adolescents medscape Aug.2001 While bipolar disorder isn't much mentioned, it does provide a good overview of the atypical antipsychotics and their use with children. includes a table of drug interactions which can be reached through the table of contents. (revamped link)

Antipsychotic Prescribing Practices for Children and Adolescents Medscape Jan. 2003 Among psychiatric inpatient youth, physicians are known to prescribe atypical antipsychotics more for aggression than for psychosis

Mood Stabilizers May Have Same Efficacy for Children With Bipolar Disorder as Adults MentalHealth Infosource

Metformin Offsets Weight Gain in Children on Psychotropics Medscape April 2002


Aripiprazole (Abilify) A Novel Atypical Antipsychotic Feb,2003 Bipolar Child Newsletter Well balanced article which includes experiences of children who were prescribed the drug.


DG DISPATCH - AACAP: Risperidone May Treat Aggression In Youths A recent study indicates that risperidone might be useful in the treatment of aggression in youths with bipolar disorder.

 Risperidone Plus Mood Stabilizer Helpful in Acute Mania Medscape July 18,2002 The combination may also be associated with the need for lower blood levels of the mood stabilizer, thus diminishing dose-related side effects associated with these agents


Can Childhood Be Normal Again-- University Hospitals' Study Looks at Preventing Manic Depression On going study is using Depakote as a prophylactic in children whose parents have bipolar disorder and who have some signs of it themselves..

Anti-Convulsant Depakote (Divalproex) May Improve Behavior In Disruptive Youths 

 


PSYCHIATRY Update- Bipolar children improve with epilepsy drug topiramate/Topomax


DG DISPATCH - APA Olanzapine Effective for Juvenile Bipolar Disorder May 18, 2000 Dr. Frazier explained, "The thing that is the most life-giving about this … is that it really quells the aggression

Medicine for Melancholy: Treating Kids with Bipolar Disorder brain.com May 24, 00 Short article on a study by Dr. Jean A. Frazier of Harvard University using olanzapine ...suggests that olanzapine is an effective monotherapy for juvenile bipolar disorder and improves patients' level of mania, depression, and psychosis


Carbamazepine Adversely Alters Serum Lipids Profile in Children  which may increase the risk of atherosclerosis.Valproic acid does not appear to have the same effect.. Medscape (outdated link)

Journal of the American Academy of Child and Adolescent Psychiatry March 1999 Case Study : Carbamazepine treatment of juvenile-onset bipolar disorder


Antiepileptic therapy in children may cause tubular renal injury News @ PharmiWeb carbamazine and valproic acid We suggest that combined therapy, and in certain cases also monotherapy longer than 10 years, results in a higher risk of tubular functional impairment," the authors conclude.

Trileptal: A Promising New Mood Stabilizer  The Bipolar Child Newsletter
Summer 2001 Vol. 8

Common Side Effect of Risperidone Not Seen with Quetiapine Treatment psychport Aug, 2001


Antidepressants

Adverse Effects From Antidepressants for Bipolar Treatment Are Common in Children Medscape June, 2003 Fifth International Conference on Bipolar Disorder Antidepressants .... cause adverse effects in more than three quarters of children within the first four months of treatment Increased cycling starting within a day of initiation of antidepressants was experienced by 79%, 70.9% experienced increased aggression, and 23.1% experienced psychotic symptoms.

FDA recommends that Paxil not be used for the treatment of pediatric major depressive disorder  June 2003 CDER FAQ FDA reviewing reports of increased suicidal risk and recommending that Paxil not be used until results are in.

Newer Antidepressants Provide Hope for Effective Drug Treatment of Depression in Children and Adolescents medscape Because of lack of efficacy and the potential for life-threatening adverse effects, neither TCAs nor MAOIs can be recommended for the treatment of depression in children and adolescents.[5]

 SSRI Therapy May Reduce Growth Rate in Children small study of only four children.  In .... two children, SSRI therapy could not be discontinued due to the psychiatric symptoms present, but their growth rate improved after somatropin therapy was begun.

Citalopram in Child and Adolescent Depression With Anxiety medscape

FDA Approves Prozac for Pediatric Depression and OCD Medscape Reuter;s Health jan 2003 Prozac is the first selective serotonin reuptake inhibitor (SSRI) to receive approval for treating depression in this patient population

Not Working

Findings Reported for Lithium and Divalproex Studies in Adolescents Mentalhealth Infosource